Cardiac & Antihypertensive

Brimonidine Tartrate + Timolol MaleateThird Party Manufacturing in India

Looking to get Brimonidine Tartrate + Timolol Maleate manufactured under your brand? Our WHO-GMP certified partner facilities support PCD franchise partners and global export opportunities structured across 25+ countries.

WHO-GMP Certified
Export Ready
PCD Franchise Available
CAS Number
70359-46-5
Drug Class
Alpha-2 Adrenergic Agonist and Beta-Blocker Combination
Molecular Formula
Combination product (C₁₁H₁₀BrN₅·C₄H₆O₆ / C₁₃H₂₄N₄O₃S·C₄H₄O₄)
Molecular Weight
Combination product
Grade Standards
IP, BP, USP
Therapeutic Category
Cardiac & Antihypertensive
MOQ
10,000 vials per batch
Dosage Forms
Eye Drops

Mechanism of Action

Brimonidine Tartrate + Timolol Maleate works by employing a dual mechanism to lower intraocular pressure. Brimonidine tartrate acts as a selective alpha-2 adrenergic receptor agonist, reducing aqueous humor production and increasing uveoscleral outflow. Timolol maleate acts as a non-selective beta-adrenergic receptor blocker, decreasing aqueous humor secretion by the ciliary epithelium without affecting pupil size. Unlike monotherapy, this combination provides a synergistic effect, achieving greater pressure reduction than either component used alone. It is highly effective and well-tolerated.

Therapeutic Uses & Indications

Therapeutic Uses

  • Open-Angle Glaucoma: Indicated for reducing intraocular pressure in patients with open-angle glaucoma who are insufficiently controlled on beta-blockers alone.
  • Ocular Hypertension: Used to manage elevated intraocular pressure and prevent progressive optic nerve damage.

Why Manufacturers Choose Brimonidine Tartrate + Timolol Maleate

This anti-glaucoma combination has high market priority due to the expanding geriatric demographic requiring chronic ocular maintenance therapy. Utilizing Brimonidine Tartrate + Timolol Maleate third party manufacturing in India ensures a reliable stream of high-margin ophthalmic products. Our production facilities are WHO-GMP certified, utilizing stabilized oxychloro complexes as advanced preservatives to meet contemporary clinical standards and avoid benzalkonium chloride sensitivities.

Dosage Forms We Manufacture

Eye Drops
0.2% w/v + 0.5% w/v

Frequently Asked Questions

What is the minimum order quantity for Brimonidine Tartrate + Timolol Maleate?
Minimum order quantity for Brimonidine Tartrate + Timolol Maleate is 10,000 vials per batch. Please contact us for bulk pricing and custom quantities.
What dosage forms of Brimonidine Tartrate + Timolol Maleate can you manufacture?
We manufacture Brimonidine Tartrate + Timolol Maleate as: Eye Drops (0.2% w/v + 0.5% w/v).
Are your manufacturing facilities WHO-GMP certified?
Yes. Celesta Healthcare works exclusively with WHO-GMP certified partner production facilities. All manufacturing batches are subject to strict quality control and documentation.
Can you manufacture Brimonidine Tartrate + Timolol Maleate for export?
Yes. We provide export-ready Brimonidine Tartrate + Timolol Maleate formulations structured across 25+ countries. We provide full export documentation including Certificate of Analysis (CoA), Certificate of Origin, and regulatory dossiers on request.
What grade standards do you follow for Brimonidine Tartrate + Timolol Maleate?
We manufacture Brimonidine Tartrate + Timolol Maleate to IP, BP, USP pharmacopoeial standards.
Third Party Manufacturing

Get Brimonidine Tartrate + Timolol Maleate made under your brand

  • WHO-GMP certified facilities
  • Quote within 24 hours
  • MOQ from 10,000 vials per batch
Get a Manufacturing QuoteWhatsApp Us Now

+91 9689237122 · replies within hours

Our Manufacturing Capabilities

  • WHO-GMP Certified Partner Plants
  • 25+ years of pharma industry experience
  • PCD Franchise with monopoly rights
  • Export support across 25+ countries
  • Small batch to commercial scale
  • Custom formulation development

Packaging Options

Three-piece dropper bottles, sterile plastic squeeze vials. Packaging customized to client brand guidelines.

Start Manufacturing Brimonidine Tartrate + Timolol Maleate Today

Celesta Healthcare provides WHO-GMP certified third-party manufacturing for Brimonidine Tartrate + Timolol Maleate across all dosage forms. PCD franchise and export orders welcome.

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