Cardiac & Antihypertensive

Brinzolamide + Timolol MaleateThird Party Manufacturing in India

Looking to get Brinzolamide + Timolol Maleate manufactured under your brand? Our WHO-GMP certified partner facilities support PCD franchise partners and global export opportunities structured across 25+ countries.

WHO-GMP Certified
Export Ready
PCD Franchise Available
CAS Number
138890-62-7
Drug Class
Carbonic anhydrase inhibitor and Beta-blocker combination
Molecular Formula
Combination product (C₁₂H₂₁N₃O₅S₃ / C₁₃H₂₄N₄O₃S·C₄H₄O₄)
Molecular Weight
Combination product
Grade Standards
IP, USP
Therapeutic Category
Cardiac & Antihypertensive
MOQ
10,000 vials per batch
Dosage Forms
Ophthalmic Suspension

Mechanism of Action

Brinzolamide + Timolol Maleate works by simultaneously suppressing aqueous humor secretion via two distinct pharmacological pathways. Brinzolamide reduces fluid secretion by blocking carbonic anhydrase enzyme activity in the ciliary processes, while timolol blocks beta-adrenergic receptors to further minimize fluid production. They work together to help the body control elevated intraocular pressure. Unlike separate drop administrations, this combination minimizes preservative exposure to the ocular surface. It is highly effective and well-tolerated.

Therapeutic Uses & Indications

Therapeutic Uses

  • Refractory Open-Angle Glaucoma: Prescribed for patients requiring multi-mechanism treatment to achieve targeted intraocular pressure reductions.
  • Ocular Hypertension Management: Used to manage high fluid pressures that do not respond to single-agent beta-blockers or prostaglandin analogs.

Why Manufacturers Choose Brinzolamide + Timolol Maleate

Brinzolamide + Timolol Maleate third party manufacturing in India is highly favored by pharmaceutical distributors due to excellent patient compliance rates and steady chronic-use market demand. Celesta oversees the rigorous formulation requirements through partner facilities that are WHO-GMP certified, ensuring optimal viscosity, particle size, and sterile batch repeatability. Adding this combination to your ophthalmic line provides an authoritative product offering manufactured under international WHO-GMP protocols.

Dosage Forms We Manufacture

Ophthalmic Suspension
1.0% + 0.5% w/v

Frequently Asked Questions

What is the minimum order quantity for Brinzolamide + Timolol Maleate?
Minimum order quantity for Brinzolamide + Timolol Maleate is 10,000 vials per batch. Please contact us for bulk pricing and custom quantities.
What dosage forms of Brinzolamide + Timolol Maleate can you manufacture?
We manufacture Brinzolamide + Timolol Maleate as: Ophthalmic Suspension (1.0% + 0.5% w/v).
Are your manufacturing facilities WHO-GMP certified?
Yes. Celesta Healthcare works exclusively with WHO-GMP certified partner production facilities. All manufacturing batches are subject to strict quality control and documentation.
Can you manufacture Brinzolamide + Timolol Maleate for export?
Yes. We provide export-ready Brinzolamide + Timolol Maleate formulations structured across 25+ countries. We provide full export documentation including Certificate of Analysis (CoA), Certificate of Origin, and regulatory dossiers on request.
What grade standards do you follow for Brinzolamide + Timolol Maleate?
We manufacture Brinzolamide + Timolol Maleate to IP, USP pharmacopoeial standards.
Third Party Manufacturing

Get Brinzolamide + Timolol Maleate made under your brand

  • WHO-GMP certified facilities
  • Quote within 24 hours
  • MOQ from 10,000 vials per batch
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+91 9689237122 · replies within hours

Our Manufacturing Capabilities

  • WHO-GMP Certified Partner Plants
  • 25+ years of pharma industry experience
  • PCD Franchise with monopoly rights
  • Export support across 25+ countries
  • Small batch to commercial scale
  • Custom formulation development

Packaging Options

Sterile dropper bottles (5ml) designed for uniform suspension drop delivery. Packaging customized to client brand guidelines.

Start Manufacturing Brinzolamide + Timolol Maleate Today

Celesta Healthcare provides WHO-GMP certified third-party manufacturing for Brinzolamide + Timolol Maleate across all dosage forms. PCD franchise and export orders welcome.

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