Cardiac & Antihypertensive

Brinzolamide + Timolol MaleateThird Party Manufacturing in India

Looking to get Brinzolamide + Timolol Maleate manufactured under your brand? Our WHO-GMP certified partner facilities support PCD franchise partners and global export opportunities structured across 25+ countries.

WHO-GMP Certified
Export Ready
PCD Franchise Available
CAS Number
138890-62-7
Drug Class
Carbonic Anhydrase Inhibitor and Beta-Blocker Combination
Molecular Formula
Combination product (C₁₂H₂₁N₃O₅S₂ / C₁₃H₂₄N₄O₃S·C₄H₄O₄)
Molecular Weight
Combination product
Grade Standards
IP, BP, USP
Therapeutic Category
Cardiac & Antihypertensive
MOQ
10,000 vials per batch
Dosage Forms
Eye Drops

Mechanism of Action

Brinzolamide + Timolol Maleate works by reducing aqueous humor production via complementary chemical pathways. Brinzolamide blocks carbonic anhydrase II, lowering bicarbonate production and fluid secretion in the ciliary processes. Timolol maleate concurrently blocks beta-adrenergic receptors in the ciliary epithelium, decreasing adenylate cyclase activity and reducing aqueous secretion. Unlike single-molecule alternatives, this dual action targets fluid production at two separate receptor sites, leading to steady intraocular pressure control. It is highly effective and well-tolerated.

Therapeutic Uses & Indications

Therapeutic Uses

  • Refractory Glaucoma: Prescribed for reduction of intraocular pressure in patients who do not achieve adequate target pressure goals on monotherapy.
  • Intraocular Pressure Surges: Used to maintain consistent pressure reduction across a 24-hour cycle in open-angle glaucoma patients.

Why Manufacturers Choose Brinzolamide + Timolol Maleate

This combination is highly sought-after in standard glaucoma protocols as it addresses the core issue of aqueous overproduction from two angles. Opting for Brinzolamide + Timolol Maleate third party manufacturing in India streamlines the production of technical ophthalmic suspensions. Our production facilities are WHO-GMP certified, maintaining strict control over pH, viscosity, and sterile compliance parameters.

Dosage Forms We Manufacture

Eye Drops
1% w/v + 0.5% w/v

Frequently Asked Questions

What is the minimum order quantity for Brinzolamide + Timolol Maleate?
Minimum order quantity for Brinzolamide + Timolol Maleate is 10,000 vials per batch. Please contact us for bulk pricing and custom quantities.
What dosage forms of Brinzolamide + Timolol Maleate can you manufacture?
We manufacture Brinzolamide + Timolol Maleate as: Eye Drops (1% w/v + 0.5% w/v).
Are your manufacturing facilities WHO-GMP certified?
Yes. Celesta Healthcare works exclusively with WHO-GMP certified partner production facilities. All manufacturing batches are subject to strict quality control and documentation.
Can you manufacture Brinzolamide + Timolol Maleate for export?
Yes. We provide export-ready Brinzolamide + Timolol Maleate formulations structured across 25+ countries. We provide full export documentation including Certificate of Analysis (CoA), Certificate of Origin, and regulatory dossiers on request.
What grade standards do you follow for Brinzolamide + Timolol Maleate?
We manufacture Brinzolamide + Timolol Maleate to IP, BP, USP pharmacopoeial standards.
Third Party Manufacturing

Get Brinzolamide + Timolol Maleate made under your brand

  • WHO-GMP certified facilities
  • Quote within 24 hours
  • MOQ from 10,000 vials per batch
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+91 9689237122 · replies within hours

Our Manufacturing Capabilities

  • WHO-GMP Certified Partner Plants
  • 25+ years of pharma industry experience
  • PCD Franchise with monopoly rights
  • Export support across 25+ countries
  • Small batch to commercial scale
  • Custom formulation development

Packaging Options

Sterile plastic dropper bottles, premium export-compliant packaging. Packaging customized to client brand guidelines.

Start Manufacturing Brinzolamide + Timolol Maleate Today

Celesta Healthcare provides WHO-GMP certified third-party manufacturing for Brinzolamide + Timolol Maleate across all dosage forms. PCD franchise and export orders welcome.

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