Cefepime HydrochlorideThird Party Manufacturing in India

Cefepime Hydrochloride (CAS 123171-59-5) works as a bactericidal agent by inhibiting the synthesis of the bacterial cell wall. The molecule selectively binds with high affinity to specific penicillin-binding proteins located on the inner membrane of the bacterial cell wall. This binding directly inhibits the transpeptidation process, which is the final cross-linking step required to build a stable peptidoglycan layer. Consequently, the bacterial cell wall loses its structural integrity, leading to cell swelling, osmotic lysis, and rapid bacterial death. Unlike earlier generation cephalosporins, Cefepime Hydrochloride possesses a zwitterionic structure that allows it to rapidly penetrate the outer membrane of Gram-negative bacteria via porin channels. It is also highly resistant to hydrolysis by many chromosomal and plasmid-mediated beta-lactamases. This makes Cefepime Hydrochloride exceptionally effective against a broad spectrum of pathogens, including both Gram-positive organisms and tough Gram-negative bacteria such as Pseudomonas aeruginosa and Enterobacteriaceae. It is widely utilized in clinical settings to manage moderate-to-severe systemic infections.

We offer specialized sterile dry powder lines for Cefepime third party manufacturing in India, delivering a range of strengths for hospital supply chains. Cefepime Hydrochloride (CAS 123171-59-5) is a highly potent fourth-generation cephalosporin injection indicated for moderate-to-severe systemic infections.

Therapeutic Uses

Cefepime Hydrochloride injection is prescribed for the treatment of:

• Moderate to Severe Pneumonia: Effective against community-acquired and nosocomial pneumonia.
• Urinary Tract Infections (UTIs): Prescribed for complicated and uncomplicated UTIs, including pyelonephritis.
• Skin and Skin Structure Infections: Used to treat complicated infections of the skin and subcutaneous tissues.
• Complicated Intra-Abdominal Infections: Administered in combination with metronidazole for deep abdominal infections.
• Empiric Therapy for Febrile Neutropenia: Utilized as monotherapy for the initial treatment of patients with fever and neutropenia.

Sourcing from a Cefepime Manufacturer

For hospital procurement agencies and export partners, selecting an experienced Cefepime manufacturer is critical to ensure batch consistency and sterile integrity. The drug must be filled in sterile dry powder vials within specialized beta-lactam zones to prevent cross-contamination.

Our manufacturing partners utilize WHO-GMP certified dedicated cephalosporin blocks. We manufacture Cefepime dry powder injections in multiple strengths (250mg, 500mg, 1g, and 2g) in compliance with WHO-GMP standards. This versatile product range supports distributors in entering hospital tenders, retail distribution, and export markets.