Respiratory & Allergy

Diphenhydramine HydrochlorideThird Party Manufacturing in India

Looking to get Diphenhydramine Hydrochloride manufactured under your brand? Our WHO-GMP certified partner facilities support PCD franchise partners and global export opportunities structured across 25+ countries.

WHO-GMP Certified
Export Ready
PCD Franchise Available
CAS Number
147-24-0
Drug Class
First-generation antihistamine
Molecular Formula
C₁₇H₂₁NO·HCl
Molecular Weight
291.82 g/mol
Grade Standards
IP, USP
Therapeutic Category
Respiratory & Allergy
MOQ
10,000 ampoules per batch
Dosage Forms
Liquid Injection

Mechanism of Action

Diphenhydramine Hydrochloride works by acting as an inverse agonist at peripheral and central H1-histamine receptors. It inhibits the physiological effects of histamine on vascular smooth muscle, bronchial passages, and gastrointestinal tracts to help the body alleviate acute allergic flare-ups. Unlike second-generation antihistamines, it crosses the blood-brain barrier readily, binding to central H1 receptors to provide predictable sedative and antiemetic outcomes. It is highly effective and well-tolerated for emergency medical applications.

Therapeutic Uses & Indications

Therapeutic Uses

  • Acute Allergic Reactions: Provides immediate systemic relief from anaphylaxis, angioedema, and severe urticaria when oral dosing is impractical.
  • Motion Sickness: Prevents and manages nausea, vomiting, and vertigo associated with motion sickness through vestibular pathways.
  • Extrapyramidal Symptoms: Treats drug-induced extrapyramidal disorders and Parkinsonian symptoms effectively.

Why Manufacturers Choose Diphenhydramine Hydrochloride

Opting for Diphenhydramine Hydrochloride third party manufacturing in India allows B2B buyers to tap into an essential emergency medicine segment. Our partner facilities are WHO-GMP certified, utilizing advanced sterilization lines to manufacture highly stable liquid parenteral formulations. Celesta provides flexible scaling and accurate chemical purity to meet rising export and regional requirements.

Dosage Forms We Manufacture

Liquid Injection
10mg/ml · 50mg/ml

Frequently Asked Questions

What is the minimum order quantity for Diphenhydramine Hydrochloride?
Minimum order quantity for Diphenhydramine Hydrochloride is 10,000 ampoules per batch. Please contact us for bulk pricing and custom quantities.
What dosage forms of Diphenhydramine Hydrochloride can you manufacture?
We manufacture Diphenhydramine Hydrochloride as: Liquid Injection (10mg/ml, 50mg/ml).
Are your manufacturing facilities WHO-GMP certified?
Yes. Celesta Healthcare works exclusively with WHO-GMP certified partner production facilities. All manufacturing batches are subject to strict quality control and documentation.
Can you manufacture Diphenhydramine Hydrochloride for export?
Yes. We provide export-ready Diphenhydramine Hydrochloride formulations structured across 25+ countries. We provide full export documentation including Certificate of Analysis (CoA), Certificate of Origin, and regulatory dossiers on request.
What grade standards do you follow for Diphenhydramine Hydrochloride?
We manufacture Diphenhydramine Hydrochloride to IP, USP pharmacopoeial standards.
Third Party Manufacturing

Get Diphenhydramine Hydrochloride made under your brand

  • WHO-GMP certified facilities
  • Quote within 24 hours
  • MOQ from 10,000 ampoules per batch
Get a Manufacturing QuoteWhatsApp Us Now

+91 9689237122 · replies within hours

Our Manufacturing Capabilities

  • WHO-GMP Certified Partner Plants
  • 25+ years of pharma industry experience
  • PCD Franchise with monopoly rights
  • Export support across 25+ countries
  • Small batch to commercial scale
  • Custom formulation development

Packaging Options

Clear glass ampoules in secure blister trays. Packaging customized to client brand guidelines.

Start Manufacturing Diphenhydramine Hydrochloride Today

Celesta Healthcare provides WHO-GMP certified third-party manufacturing for Diphenhydramine Hydrochloride across all dosage forms. PCD franchise and export orders welcome.

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