EthamsylateThird Party Manufacturing in India

Ethamsylate works by enhancing capillary wall resistance and improving platelet adhesion, making it an effective hemostatic agent. It reduces capillary exudation and blood loss by stabilizing the endothelial lining of small blood vessels. The drug increases platelet adhesiveness at sites of vascular injury, promoting the formation of a robust platelet plug during the initial phase of hemostasis. Ethamsylate also inhibits prostaglandin synthesis, particularly prostacyclin, a potent vasodilator and platelet disaggregation promoter. By reducing prostacyclin levels, Ethamsylate creates a favorable environment for platelet aggregation and vasoconstriction at injury sites. This dual mechanism — capillary stabilization and platelet function enhancement — distinguishes it from other hemostatic agents like tranexamic acid, which works through antifibrinolytic pathways. Its favorable safety profile and quick onset of action make it suitable for both prophylactic and therapeutic use in bleeding disorders across a wide patient population.

Ethamsylate (CAS 2624-44-4) is a widely prescribed synthetic hemostatic agent used to prevent and treat capillary bleeding. Celesta offers high-quality options for Ethamsylate third party manufacturing in India, supplying domestic and international markets with sterile injectable formulations.

Therapeutic Uses

Ethamsylate is prescribed for the treatment of:

• Surgical Bleeding Prophylaxis: Administered before and after surgical procedures — including dental, ophthalmic, ENT, and gynecological surgeries — to reduce intraoperative and postoperative blood loss.
• Menorrhagia: Used for managing excessive menstrual bleeding, reducing blood loss and improving quality of life in women with heavy periods.
• Neonatal Intraventricular Hemorrhage: Administered to prevent periventricular hemorrhage in low birth-weight preterm neonates.
• Hematuria, Epistaxis, and Hemoptysis: Used to control bleeding from the urinary tract, nasal passages, and respiratory tract.
• Postpartum Hemorrhage: The drug is employed to control excessive bleeding following childbirth.

Choosing an Ethamsylate Manufacturer in India

Ethamsylate is a high-demand molecule in the pharmaceutical manufacturing market due to its established safety profile, multiple dosage forms, and consistent prescription volume across gynecology, surgery, and pediatrics. Producing sterile Ethamsylate injections (250mg/2ml) requires advanced liquid filling lines and strict quality control. Sourcing from a WHO-GMP certified manufacturer in India guarantees high-purity, stable formulations that prevent degradation and maintain stability. Our partner WHO-GMP certified facilities ensure full compliance with IP, BP, and USP standards, making this hemostatic injection highly suitable for hospital tenders, emergency procurement, and export markets.

To place an order or discuss customization, please contact our team. You can view our hematological portfolio on our manufacturing listing page or read about our capabilities on our contract manufacturing page.

This makes Ethamsylate one of the most sought-after hemostatic agents for third party manufacturing in India, with consistent demand from PCD franchise operators and export-oriented pharmaceutical companies.