Antidiabetic

Metformin HydrochlorideThird Party Manufacturing in India

Looking to get Metformin Hydrochloride manufactured under your brand? Our WHO-GMP certified partner facilities support PCD franchise partners and global export opportunities structured across 25+ countries.

WHO-GMP Certified
Export Ready
PCD Franchise Available
CAS Number
1115-70-4
Drug Class
Biguanide antidiabetic
Molecular Formula
C₄H₁₂ClN₅
Molecular Weight
165.62 g/mol
Grade Standards
IP, BP, USP, EP
Therapeutic Category
Antidiabetic
MOQ
10,000 tablets per batch
Dosage Forms
Tablet, Sustained Release (SR) Tablet

Mechanism of Action

Metformin Hydrochloride works by decreasing hepatic glucose production and improving insulin sensitivity.

It activates AMP-activated protein kinase (AMPK) in the liver, which suppresses gluconeogenesis (the production of glucose) and enhances peripheral glucose uptake and utilization by muscles. This dual action helps the body respond better to its own insulin and lowers blood glucose levels without stimulating additional insulin secretion.

Unlike sulfonylureas, Metformin Hydrochloride does not cause hypoglycemia when used as monotherapy. It is highly effective and well-tolerated for adult and pediatric patients with type 2 diabetes mellitus, often leading to weight neutrality or modest weight loss.

Therapeutic Uses & Indications

Therapeutic Uses

Metformin Hydrochloride is prescribed for the treatment of:

  • Type 2 Diabetes Mellitus: Used as a first-line therapy alongside diet and exercise to improve glycemic control in adults and children.
  • Polycystic Ovary Syndrome (PCOS): Frequently prescribed off-label to manage insulin resistance and improve ovulatory function in women with PCOS.
  • Metabolic Syndrome: Used to manage metabolic risks associated with certain conditions or medications, improving overall insulin sensitivity.

Why Manufacturers Choose Metformin Hydrochloride

Metformin Hydrochloride is the cornerstone of type 2 diabetes management globally, ensuring massive, sustained demand. Its established safety profile, efficacy, and suitability for long-term use make it a staple in any antidiabetic portfolio.

This makes Metformin Hydrochloride one of the most sought-after molecules for third party manufacturing in India, with consistent demand from PCD franchise operators and export-oriented companies looking to supply high-volume, essential medications.

Dosage Forms We Manufacture

Tablet
500mg · 850mg · 1000mg
Sustained Release (SR) Tablet
500mg · 850mg · 1000mg

Frequently Asked Questions

What is the minimum order quantity for Metformin Hydrochloride?
Minimum order quantity for Metformin Hydrochloride is 10,000 tablets per batch. Please contact us for bulk pricing and custom quantities.
What dosage forms of Metformin Hydrochloride can you manufacture?
We manufacture Metformin Hydrochloride as: Tablet (500mg, 850mg, 1000mg); Sustained Release (SR) Tablet (500mg, 850mg, 1000mg).
Are your manufacturing facilities WHO-GMP certified?
Yes. Celesta Healthcare works exclusively with WHO-GMP certified partner production facilities. All manufacturing batches are subject to strict quality control and documentation.
Can you manufacture Metformin Hydrochloride for export?
Yes. We provide export-ready Metformin Hydrochloride formulations structured across 25+ countries. We provide full export documentation including Certificate of Analysis (CoA), Certificate of Origin, and regulatory dossiers on request.
What grade standards do you follow for Metformin Hydrochloride?
We manufacture Metformin Hydrochloride to IP, BP, USP, EP pharmacopoeial standards.
Third Party Manufacturing

Get Metformin Hydrochloride made under your brand

  • WHO-GMP certified facilities
  • Quote within 24 hours
  • MOQ from 10,000 tablets per batch
Get a Manufacturing QuoteWhatsApp Us Now

+91 9689237122 · replies within hours

Our Manufacturing Capabilities

  • WHO-GMP Certified Partner Plants
  • 25+ years of pharma industry experience
  • PCD Franchise with monopoly rights
  • Export support across 25+ countries
  • Small batch to commercial scale
  • Custom formulation development

Packaging Options

Blister pack (Alu-PVC), Strip pack, HDPE bottle. Packaging customized to client brand guidelines.

Start Manufacturing Metformin Hydrochloride Today

Celesta Healthcare provides WHO-GMP certified third-party manufacturing for Metformin Hydrochloride across all dosage forms. PCD franchise and export orders welcome.

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