Oncology & Anticancer

MethotrexateThird Party Manufacturing in India

Looking to get Methotrexate manufactured under your brand? Our WHO-GMP certified partner facilities support PCD franchise partners and global export opportunities structured across 25+ countries.

WHO-GMP Certified
Export Ready
PCD Franchise Available
CAS Number
59-05-2
Drug Class
Antimetabolite (Folate analog)
Molecular Formula
C₂₀H₂₂N₈O₅
Molecular Weight
454.44 g/mol
Grade Standards
IP, USP, BP
Therapeutic Category
Oncology & Anticancer
MOQ
Contact us for MOQ — varies by strength and dosage form
Dosage Forms
Injection

Mechanism of Action

Methotrexate works by competitively inhibiting the enzyme dihydrofolate reductase, which is essential for the synthesis of tetrahydrofolate. This inhibition disrupts the production of purines and pyrimidines, crucial components of DNA and RNA.

This cytotoxic effect helps the body halt the rapid division of cancer cells and suppresses immune system overactivity.

Unlike targeted biological therapies, Methotrexate provides a broad antimetabolite action. It is highly effective for treating various neoplastic diseases and severe autoimmune conditions.

Therapeutic Uses & Indications

Therapeutic Uses

Methotrexate is prescribed for the treatment of:

  • Neoplastic Diseases: Treatment of acute lymphoblastic leukemia, breast cancer, and lymphomas.
  • Rheumatoid Arthritis: Management of severe, active rheumatoid arthritis in adults.
  • Severe Psoriasis: Control of severe, disabling psoriasis when other treatments fail.

Why Manufacturers Choose Methotrexate

Due to its broad therapeutic application in both oncology and rheumatology, Methotrexate remains a cornerstone molecule. The requirement for various strengths and high-quality sterile manufacturing makes it a premium product.

This makes Methotrexate a highly sought-after product for third party manufacturing in India, serving global oncology and autoimmune therapy demands.

Dosage Forms We Manufacture

Injection
15mg/3ml · 50mg · 100mg · 250mg · 500mg · 1000mg

Frequently Asked Questions

What is the minimum order quantity for Methotrexate?
Minimum order quantity for Methotrexate is Contact us for MOQ — varies by strength and dosage form. Please contact us for bulk pricing and custom quantities.
What dosage forms of Methotrexate can you manufacture?
We manufacture Methotrexate as: Injection (15mg/3ml, 50mg, 100mg, 250mg, 500mg, 1000mg).
Are your manufacturing facilities WHO-GMP certified?
Yes. Celesta Healthcare works exclusively with WHO-GMP certified partner production facilities. All manufacturing batches are subject to strict quality control and documentation.
Can you manufacture Methotrexate for export?
Yes. We provide export-ready Methotrexate formulations structured across 25+ countries. We provide full export documentation including Certificate of Analysis (CoA), Certificate of Origin, and regulatory dossiers on request.
What grade standards do you follow for Methotrexate?
We manufacture Methotrexate to IP, USP, BP pharmacopoeial standards.
Third Party Manufacturing

Get Methotrexate made under your brand

  • WHO-GMP certified facilities
  • Quote within 24 hours
  • Low MOQ, export ready
Get a Manufacturing QuoteWhatsApp Us Now

+91 9689237122 · replies within hours

Our Manufacturing Capabilities

  • WHO-GMP Certified Partner Plants
  • 25+ years of pharma industry experience
  • PCD Franchise with monopoly rights
  • Export support across 25+ countries
  • Small batch to commercial scale
  • Custom formulation development

Packaging Options

Vials in mono cartons. Packaging customized to client brand guidelines.

Start Manufacturing Methotrexate Today

Celesta Healthcare provides WHO-GMP certified third-party manufacturing for Methotrexate across all dosage forms. PCD franchise and export orders welcome.

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