Respiratory & Allergy

Paracetamol + Phenylephrine hydrochloride + Caffeine + DiphenhydramineThird Party Manufacturing in India

Looking to get Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine manufactured under your brand? Our WHO-GMP certified partner facilities support PCD franchise partners and global export opportunities structured across 25+ countries.

WHO-GMP Certified
Export Ready
PCD Franchise Available
CAS Number
103-90-2
Drug Class
Multi-symptom cold and flu combination
Molecular Formula
Combination product (C₈H₉NO₂ / C₉H₁₂ClNO / C₈H₁₀N₄O₂ / C₁₇H₂₁NO)
Molecular Weight
Combination product
Grade Standards
IP
Therapeutic Category
Respiratory & Allergy
MOQ
20,000 tablets per batch
Dosage Forms
Tablet

Mechanism of Action

Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine works by utilizing a four-pronged therapeutic strategy. Paracetamol inhibits prostaglandin synthesis to reduce pain and fever, phenylephrine constricts nasal vessels to clear airways, diphenhydramine blocks central and peripheral H1 histamine receptors to halt allergy symptoms and rhinorrhea, and caffeine acts as a central nervous system stimulant and analgesic adjuvant. Unlike standard antihistamine mixtures, caffeine counteracts the sedative properties of diphenhydramine while accelerating pain relief. It is highly effective and well-tolerated for daytime symptom management.

Therapeutic Uses & Indications

Therapeutic Uses

  • Severe Cold and Flu: Relieves systemic body aches, high fever, and extreme nasal congestion.
  • Sinus Headache: Alleviates intense sinus pressure pain through caffeine-induced vasoconstriction and paracetamol analgesia.
  • Allergic Vasomotor Rhinitis: Suppresses severe running nose, itchy throat, and continuous sneezing.

Why Manufacturers Choose Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine

This premium, four-ingredient formulation offers comprehensive symptom control, making it highly attractive to consumers seeking fast multi-symptom relief. Opting for Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine third party manufacturing in India via Celesta ensures stable formulation of complex multi-API tablets. Our manufacturing partners manage CAS 103-90-2 primary combinations within advanced WHO-GMP certified facilities. These WHO-GMP standards prevent cross-contamination and ensure exact dosing accuracy for all four active ingredients.

Dosage Forms We Manufacture

Tablet
500mg + 5mg + 30mg + 25mg

Frequently Asked Questions

What is the minimum order quantity for Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine?
Minimum order quantity for Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine is 20,000 tablets per batch. Please contact us for bulk pricing and custom quantities.
What dosage forms of Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine can you manufacture?
We manufacture Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine as: Tablet (500mg + 5mg + 30mg + 25mg).
Are your manufacturing facilities WHO-GMP certified?
Yes. Celesta Healthcare works exclusively with WHO-GMP certified partner production facilities. All manufacturing batches are subject to strict quality control and documentation.
Can you manufacture Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine for export?
Yes. We provide export-ready Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine formulations structured across 25+ countries. We provide full export documentation including Certificate of Analysis (CoA), Certificate of Origin, and regulatory dossiers on request.
What grade standards do you follow for Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine?
We manufacture Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine to IP pharmacopoeial standards.
Third Party Manufacturing

Get Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine made under your brand

  • WHO-GMP certified facilities
  • Quote within 24 hours
  • MOQ from 20,000 tablets per batch
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Our Manufacturing Capabilities

  • WHO-GMP Certified Partner Plants
  • 25+ years of pharma industry experience
  • PCD Franchise with monopoly rights
  • Export support across 25+ countries
  • Small batch to commercial scale
  • Custom formulation development

Packaging Options

Blister pack (Alu-Alu), Strip pack, customized blister sheets. Packaging customized to client brand guidelines.

Start Manufacturing Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine Today

Celesta Healthcare provides WHO-GMP certified third-party manufacturing for Paracetamol + Phenylephrine hydrochloride + Caffeine + Diphenhydramine across all dosage forms. PCD franchise and export orders welcome.

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