Antibiotic & Anti-infective

Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium PhosphateThird Party Manufacturing in India

Looking to get Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate manufactured under your brand? Our WHO-GMP certified partner facilities support PCD franchise partners and global export opportunities structured across 25+ countries.

WHO-GMP Certified
Export Ready
PCD Franchise Available
CAS Number
1405-20-5
Drug Class
Corticosteroid and antibacterial combination
Molecular Formula
Combination product (C₅₆H₉₈N₁₆O₁₃·H₂SO₄ / C₁₁H₁₂Cl₂N₂O₅ / C₂₂H₂₈FNa₂O₈P)
Molecular Weight
Combination product
Grade Standards
IP, BP, USP
Therapeutic Category
Antibiotic & Anti-infective
MOQ
10,000 vials per batch
Dosage Forms
Eye/Ear Drops

Mechanism of Action

Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate works by concurrently neutralizing bacterial proliferation and suppressing host inflammatory cascades. Polymyxin B disrupts the lipid architecture of Gram-negative bacterial outer membranes, inducing structural collapse. Chloramphenicol inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, suppressing Gram-positive and Gram-negative replication. Dexamethasone Sodium Phosphate, a potent corticosteroid, inhibits phospholipase A2 to block the synthesis of arachidonic acid metabolites, thereby suppressing ocular edema, capillary dilation, and leukocyte migration. Unlike standalone antibiotics, this multi-ingredient agent resolves painful inflammatory symptoms while maintaining definitive antimicrobial control. It is highly effective and well-tolerated.

Therapeutic Uses & Indications

Therapeutic Uses

  • Infectious Ocular Inflammation: Treats steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva where secondary bacterial infection risks exist.
  • Chronic Otitis Externa: Manages severe inflammation, swelling, and bacterial colonization within the external auditory meatus.
  • Post-Surgical Inflammatory Prophylaxis: Prevents postoperative microbial contamination while minimizing surgical tissue edema.

Why Manufacturers Choose Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate

Ophthalmic combinations matching these specific parameters are highly valued by clinical professionals who prefer writing a comprehensive solution for complex presentation cases. Our partner production hubs guarantee strict component segregation, precise chemical scaling matching CAS number 1405-20-5 criteria, and validate sterile fills under WHO-GMP certified standards. Securing your Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate third party manufacturing in India through Celesta ensures top-tier quality control for global compliance.

Dosage Forms We Manufacture

Eye/Ear Drops
5000 IU + 4mg + 1mg per ml · 5000 IU + 10mg + 1mg per ml

Frequently Asked Questions

What is the minimum order quantity for Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate?
Minimum order quantity for Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate is 10,000 vials per batch. Please contact us for bulk pricing and custom quantities.
What dosage forms of Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate can you manufacture?
We manufacture Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate as: Eye/Ear Drops (5000 IU + 4mg + 1mg per ml, 5000 IU + 10mg + 1mg per ml).
Are your manufacturing facilities WHO-GMP certified?
Yes. Celesta Healthcare works exclusively with WHO-GMP certified partner production facilities. All manufacturing batches are subject to strict quality control and documentation.
Can you manufacture Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate for export?
Yes. We provide export-ready Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate formulations structured across 25+ countries. We provide full export documentation including Certificate of Analysis (CoA), Certificate of Origin, and regulatory dossiers on request.
What grade standards do you follow for Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate?
We manufacture Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate to IP, BP, USP pharmacopoeial standards.
Third Party Manufacturing

Get Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate made under your brand

  • WHO-GMP certified facilities
  • Quote within 24 hours
  • MOQ from 10,000 vials per batch
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Our Manufacturing Capabilities

  • WHO-GMP Certified Partner Plants
  • 25+ years of pharma industry experience
  • PCD Franchise with monopoly rights
  • Export support across 25+ countries
  • Small batch to commercial scale
  • Custom formulation development

Packaging Options

Aseptic plastic dropper bottles with child-resistant caps. Packaging customized to client brand guidelines.

Start Manufacturing Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate Today

Celesta Healthcare provides WHO-GMP certified third-party manufacturing for Polymyxin B Sulfate + Chloramphenicol + Dexamethasone Sodium Phosphate across all dosage forms. PCD franchise and export orders welcome.

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