Sodium Chloride 0.22% + Dextrose 5% InfusionThird Party Manufacturing in India

Sodium Chloride 0.22% + Dextrose 5% Infusion is a hypotonic crystalloid solution used for maintenance fluid therapy. The 0.22% sodium chloride concentration provides a hypotonic saline solution that delivers free water along with a modest amount of sodium and chloride for daily electrolyte maintenance. The dextrose 5% component provides a caloric source, supplying approximately 170 kcal per litre, which helps reduce protein catabolism and prevents ketosis in patients who are nil by mouth. When administered intravenously, the solution distributes throughout the extracellular fluid compartment. The dextrose is rapidly metabolised, leaving the hypotonic saline to provide free water for cellular hydration. This formulation is particularly suitable for paediatric patients and adults requiring maintenance fluids, as the sodium concentration closely matches daily maintenance requirements of approximately 2-4 mEq/kg per day.

Therapeutic Uses

Sodium Chloride 0.22% + Dextrose 5% Infusion is prescribed for:

• Maintenance Fluid Therapy: Provides daily water and electrolyte requirements for patients who cannot maintain adequate oral intake.
• Paediatric Maintenance: Particularly suitable for children requiring maintenance intravenous fluids, as the hypotonic formulation reduces the risk of fluid overload.
• Post-Operative Hydration: Used to maintain hydration in surgical patients during the immediate post-operative period.
• Dehydration Management: Mild to moderate dehydration where both water and caloric supplementation are needed.

Why Manufacturers Choose This Formulation

Sodium Chloride 0.22% + Dextrose 5% Infusion is a standard maintenance IV fluid used extensively in hospitals across India. It is a high-volume, essential hospital supply product with predictable year-round demand. Indian manufacturers with WHO-GMP certified LVP production lines can produce this cost-effectively at scale. The product is a core item in hospital tenders and institutional supply contracts, making it a reliable volume driver for PCD franchise operators and institutional suppliers.