PROGE ONE 200 SOFT GEL CAP
Each soft gelatin capsule contains:Progesterone IP 200 mg(natural micronised)Excipients q.s
| Composition | Each soft gelatin capsule contains:Progesterone IP 200 mg(natural micronised)Excipients q.s |
| Packing | BLISTER CLEAR PVC - 10*10 |
| MRP | ₹361 |
Product Overview
PROGE ONE 200 Soft Gelatin Capsule delivers bioidentical, natural micronised progesterone formulated for optimal absorption and systemic tolerability. It plays an essential role in structural endometrial support and the medical management of hormonal imbalances.
Indications
- Hormone Replacement Therapy (HRT): Combats endometrial hyperplasia in postmenopausal women receiving concurrent estrogen therapy.
- Secondary Amenorrhea: Restores normal menstrual cycles caused by endogenous luteal phase deficiency.
- Pregnancy Support: Prophylactic administration to prevent recurrent threatened abortions and preterm labor.
Dosage & Administration
The standard dosage is 200 mg daily, typically administered orally at bedtime to minimize transient drowsiness. Alternatively, it can be administered vaginally if systemic side effects restrict oral use, following strict clinical guidance.
Adverse Effects
Common occurrences include somnolence, dizziness, headache, breast tenderness, abdominal bloating, and intermittent spotting.
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Contraindications
Contraindicated in individuals with active deep vein thrombosis, pulmonary embolism, a history of thromboembolic disease, undiagnosed abnormal genital bleeding, severe hepatic impairment, or known/suspected breast or genital malignancies.
Warnings & Precautions
Perform a complete medical and family history check before initiating therapy. Monitor closely for early signs of thromboembolic disorders or visual changes, and use with caution in patients with asthma, migraine, or cardiac dysfunction.
Drug Interactions
Metabolism is accelerated by strong hepatic CYP450 enzyme inducers such as rifampin, carbamazepine, and phenobarbital, which may lower therapeutic serum levels. Aminoglutethimide significantly decreases progesterone concentrations.
Storage Instructions
Store below 25°C in a dry place. Protect from high heat, direct sunlight, and freezing conditions.
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