EGNACARE-PLUS

Each Film Coated Tablet Contains: L-5 Methyltetrahydrofalate 1000mcg Excipients q.s.

DRUGHAEMATINIC
CompositionEach Film Coated Tablet Contains: L-5 Methyltetrahydrofalate 1000mcg Excipients q.s.
PackingALU ALU - 10*10
MRP₹38

Product Overview

EGNACARE-PLUS is an advanced, biologically active folate supplement featuring 1000mcg of L-5-Methyltetrahydrofolate (L-methylfolate). Unlike standard folic acid, it bypasses complex enzymatic steps, offering immediate bioavailability for vital cellular processes and red blood cell production. It is highly valued in gynaecology, neurology, and psychiatry sectors, making it a lucrative specialty addition for pharma distributors.

Indications

EGNACARE-PLUS is clinically indicated for:

  • MTHFR Polymorphism Management: Supplying active folate to individuals who cannot metabolize regular synthetic folic acid.
  • Hyperhomocysteine Management: Reducing elevated cardiovascular and neurological risks by lowering blood homocysteine levels.
  • Prenatal Nutritional Care: Lowering the incidence of neural tube defects (NTDs) during early fetal development.
  • Adjunctive Mood Management: Enhancing therapeutic outcomes when combined with standard antidepressant regimens for major depressive disorder.

Dosage & Administration

Adults: 1 tablet daily, taken with or without food, or as directed by an obstetrician or healthcare professional.

Adverse Effects

This endogenous molecule is extremely well tolerated. Rare side effects may include:

  • Mild gastrointestinal disturbances or gas
  • Allergic skin rash (infrequent)
  • Sleep pattern shifts or mild irritability at high doses
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Contraindications

Contraindicated in patients with a history of hypersensitivity to L-methylfolate or any component excipients. Do not use as a standalone therapy for undiagnosed pernicious or vitamin B12-deficiency anemia, as folate can mask underlying neurological issues.

Warnings & Precautions

Before initiating therapy, evaluate Vitamin B12 levels to avoid masking potential macrocytic anemias. Dosage adjustments should be monitored carefully in patients with a history of convulsive disorders.

Drug Interactions

High doses may reduce the serum concentrations of anticonvulsant medications (such as phenytoin, fosphenytoin, and phenobarbital). Antifolate agents (like methotrexate or pyrimethamine) can interfere with folate activity.

Storage Instructions

Store below 30°C in a dry place. Protect from excessive light, heat, and moisture exposure.

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