CITROZ 200 (NEW)

Each hard gelatin capsule contains: Itraconazole BP 200mg (As Pellets) Excipients q.s. Approved colour used in empty capsule shells

DRUGDERMA
CompositionEach hard gelatin capsule contains: Itraconazole BP 200mg (As Pellets) Excipients q.s. Approved colour used in empty capsule shells
PackingALU ALU - 10*1*10
MRP₹206

Product Overview

CITROZ 200 is a high-potency systemic antifungal agent designed to treat deep-seated and superficial fungal infections effectively. Formulated as premium pellets inside hard gelatin capsules, it ensures superior bioavailability and consistent therapeutic action. It is highly trusted for treating fungal nail infections, ringworm, and systemic mycoses.

Indications

This capsule formulation is indicated for systemic and cutaneous fungal infections, including:

  • Onychomycosis: Fungal infections affecting the fingernails or toenails.
  • Tinea Infections: Severe cases of Tinea corporis (ringworm), Tinea cruris (jock itch), and Tinea pedis (athlete's foot).
  • Systemic Mycoses: Aspergillosis, Blastomycosis, and Histoplasmosis.

Dosage & Administration

The adult dosage typically ranges from 100 mg to 200 mg once daily. For optimal absorption, the capsule must be swallowed whole immediately after a full, main meal. The treatment duration varies depending on the specific infection type and clinical response.

Adverse Effects

Reported side effects may include:

  • Gastrointestinal upset, including nausea, vomiting, or diarrhea
  • Headache or transient dizziness
  • Elevations in liver enzymes
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Contraindications

Contraindicated in patients with ventricular dysfunction (such as chronic heart failure), known hypersensitivity to azole antifungals, or during pregnancy. Co-administration with certain CYP3A4 substrates is strictly prohibited.

Warnings & Precautions

Monitor liver function tests periodically during extended treatment courses. Caution is advised in patients with pre-existing hepatic or renal impairment. If symptoms indicative of hepatitis or congestive heart failure occur, discontinue use immediately and consult a physician.

Drug Interactions

Co-administration with gastric acid neutralizers (antacids, H2 blockers, PPIs) markedly lowers Itraconazole absorption. Itraconazole can significantly increase plasma levels of Statins, Warfarin, Digoxin, and Cyclosporine by inhibiting their clearance pathways.

Storage Instructions

Store below 25°C in a dry place. Protect from heat, light, and ambient moisture. Keep out of reach of children.

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