ESOMAG-D
Each hard gelatin capsule contains: Esomeprazole Magnesium IP (as Trihydrate) Eq. to Esomeprazole 40mg (as enteric coated pellets) Domperidone IP 30mg (as sustained release pellets) Excipients q.s.
| Composition | Each hard gelatin capsule contains: Esomeprazole Magnesium IP (as Trihydrate) Eq. to Esomeprazole 40mg (as enteric coated pellets) Domperidone IP 30mg (as sustained release pellets) Excipients q.s. |
| Packing | ALU ALU - 10*10 |
| MRP | ₹121 |
Product Overview
ESOMAG-D combines a powerful proton pump inhibitor with a sustained-release prokinetic agent to manage complex acid reflux disorders. This dual-action formulation addresses both excessive acid production and delayed gastric emptying to provide comprehensive relief from bloating and heartburn. It is a vital, high-growth asset for gastro-focused pharmaceutical distribution networks across India.
Indications
ESOMAG-D is indicated for the comprehensive relief of:
- Gastroesophageal Reflux Disease (GERD): Manages severe reflux symptoms that show inadequate response to PPI monotherapy.
- Functional Dyspepsia: Addresses complex upper GI distress presenting as early satiety, postprandial fullness, and bloating.
- Reflux Esophagitis: Heals mucosal damage while managing associated nausea and upper abdominal discomfort.
- Chronic Gastritis: Controls irritation triggered by hyperacidity and delayed gastric emptying.
Dosage & Administration
Adults: 1 capsule daily, taken orally 30 minutes before the morning meal. Swallow the capsule whole—do not chew or open the capsule, as this compromises the sustained-release mechanism of the pellets.
Adverse Effects
Observed clinical side effects may include:
- Dry mouth or altered taste
- Headache or temporary dizziness
- Gastrointestinal disturbances like mild diarrhea or cramps
- Transient hyperprolactinemia (rare)
View Complete Medical Information
Contraindications
Contraindicated in patients with known hypersensitivity to either molecule, prolactin-releasing pituitary tumors, gastrointestinal hemorrhage, mechanical bowel obstructions, or cardiac conduction prolongations (such as long QT intervals).
Warnings & Precautions
Prolonged use requires monitoring for hypomagnesemia and vitamin B12 malabsorption. Due to the presence of domperidone, exercise caution in elderly patients with pre-existing cardiovascular vulnerabilities or arrhythmias.
Drug Interactions
Concomitant use with strong CYP3A4 inhibitors (like ketoconazole, erythromycin, or clarithromycin) is contraindicated, as they can elevate domperidone concentrations. May alter the absorption of pH-dependent medications such as iron salts and ketoconazole.
Storage Instructions
Store below 25°C in a dry place. Protect from light exposure and environmental moisture.
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